Welcome to MSE Lab

Our research focused on microbial systematics and evolution. Based on the next-generation sequencing techniques and the increasing genomic data, we attempted to investigate the evolution and speciation of some specific taxa, by using phylogenomic and comparative genomic approaches; reveal the evolutionary history of the relative enzymes belonging to various metabolic pathways; investigate the ecological adaptation mechanisms of prokaryotes from genomic and proteomic level.

"Nothing in Biology Makes Sense Except in the Light of Evolution"

--Theodosius Dobzhansky

Bulletin Board

《生物统计学原理》正式出版!

本书针对包括生物学在内的非数学专业读者学习统计学的痛点,在内容上强调统计分析方法背后的数学原理。作者提供了数学公式完整的推导过程,并附上必要的文字解释,填补文字和数学表达上的逻辑缺口,力求降低阅读和理解的难度。同时结合应用的需要,本书介绍的每一个统计分析方法,都通过例题呈现了R软件的操作过程,旨在让读者了解统计分析方法流程的同时掌握方法背后的基本逻辑。

购买地址:华中科技大学天猫旗舰店


Nov. 22, 2024, 9:20 a.m.

Lolamicin - a new Gram-negative-selective antibiotic

Lolamicin, targeting the lipoprotein transport system, has activity against a panel of more than 130 multidrug-resistant clinical isolates, shows efficacy in multiple mouse models of acute pneumonia and septicaemia infection, and spares the gut microbiome in mice, preventing secondary infection with Clostridioides difficile.

from: Muñoz et al., Nature. 2024. DOI:10.1038/s41586-024-07502-0


June 3, 2024, 9:45 a.m.

Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes

The authors found that eukaryotes are placed, with high confidence, as a well-nested clade within Asgard archaea and as a sister lineage to Hodarchaeales, a newly proposed order within Heimdallarchaeia.

from: Eme et al., Nature. 2023; 618(7967): 992-999. DOI:10.1038/s41586-023-06186-2


Aug. 26, 2023, 2:14 p.m.